Prominent psychologist Jordan Peterson has undergone recent treatment for a drug habit. He has found it impossible to quit taking clonazepam voluntarily, though he insists that his problem is physical dependence and not addiction.
I hope he will find an effective treatment soon. In the meantime, his dependence raises an interesting question: How should we label drug habits?
The habitual character of drug use does not reveal itself for many drugs and most drug users. Yet in posting a description of mental effort, I mentioned that some kinds of voluntary learning change to automatic behavior, passing from voluntary cortical control to involuntary striatal control. This can occur with drug use, too.
Addiction involves learning. The search for the origin of addiction in each drug user’s brain has lately focused on synaptic plasticity, both LTP and its cousin, long-term depression or LTD.
The idea occurred to brain researchers a while ago. Here’s one review from Kauer and Malenka and an updated view from Lüscher.
Drug experimentation is not uncommon among writers, artists, scientists, and physicians, though few seem to become addicted. Famous exceptions are Sigmund Freud, who never forsook his everpresent cigars other than briefly during treatment for oral cancer, and Mark Twain, who was moved by cardiac pains rather than cancer to try smoking fewer than 40 per day.
The term “addiction” is still common, but DSM-V abandoned the label in favor of “substance use disorder”. An addict bears a stigma, and even substance abuse has moral overtones.